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1

The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B negatively regulate cell proliferation through the activation of cyclin-dependent kinase inhibitor 2b (Cdkn2b) and Cdkn1a expression

Ji Hoon Yu, Bing-Mei Zhu, Mark Wickre, Gregory Riedlinger, Weiping Chen, Atsushi Hosui, Gertraud W. Robinson, Lothar Hennighausen

Journal:

Year:

2010

Language:

english

File:

PDF, 841 KB

english, 2010

2

SOCS3 Protein Developmentally Regulates the Chemokine Receptor CXCR4-FAK Signaling Pathway during B Lymphopoiesis

Yi Le, Bing-Mei Zhu, Brendan Harley, Shin-Young Park, Takashi Kobayashi, John P. Manis, Hongbo R. Luo, Akihiko Yoshimura, Lothar Hennighausen, Leslie E. Silberstein

Journal:

Year:

2007

Language:

english

File:

PDF, 1.39 MB

english, 2007

3

Loss of connexin 26 in mammary epithelium during early but not during late pregnancy results in unscheduled apoptosis and impaired development

Céline Bry, Karen Maass, Keiko Miyoshi, Klaus Willecke, Thomas Ott, Gertraud W Robinson, Lothar Hennighausen

Journal:

Developmental Biology

Year:

2004

Language:

english

File:

PDF, 1.34 MB

english, 2004

4

The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses

Bell, Bryan D, Kitajima, Masayuki, Larson, Ryan P, Stoklasek, Thomas A, Dang, Kristen, Sakamoto, Kazuhito, Wagner, Kay-Uwe, Reizis, Boris, Hennighausen, Lothar, Ziegler, Steven F

Journal:

Nature Immunology

Year:

2013

Language:

english

File:

PDF, 911 KB

english, 2013

5

The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice

Furth, Priscilla A., Hennighausen, Lothar, Baker, Carl, Beatty, Barbara, Woycick, Rick

Journal:

Nucleic Acids Research

Year:

1991

Language:

english

File:

PDF, 395 KB

english, 1991

6

Primary cancer cell culture: mammary-optimized versus conditional-reprogramming

Alamri, Ahmad M., Kang, Keunsoo, Groeneveld, Svenja, Wang, Weisheng, Zhong, Xiaogang, Kallakury, Bhaskar V.s., Hennighausen, Lothar, Liu, Xuefeng, Furth, Priscilla A.

Journal:

Endocrine Related Cancer

Year:

2016

Language:

english

File:

PDF, 12.89 MB

english, 2016

7

Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2

Lau-Corona, Dana, Bae, Woo Kyun, Hennighausen, Lothar, Waxman, David J., Zhong, Xiao-bo

Journal:

Year:

2020

File:

PDF, 8.52 MB

2020

8

Understanding mammary gland development through the imbalanced expression of growth regulators

Gertraud W. Robinson, Gilbert H. Smith, Daniel Gallahan, Andreas Zimmer, Priscilla A. Furth, Lothar Hennighausen

Journal:

Developmental Dynamics

Year:

1996

Language:

english

File:

PDF, 1.90 MB

english, 1996

9

Socs 3 modulates the activity of the transcription factor Stat3 in mammary tissue and controls alveolar homeostasis

Gertraud W. Robinson, Margit Pacher-Zavisin, Bing Mei Zhu, Akihiko Yoshimura, Lothar Hennighausen

Journal:

Developmental Dynamics

Year:

2007

Language:

english

File:

PDF, 637 KB

english, 2007

10

Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia

Andrea Hoelbl, Christian Schuster, Boris Kovacic, Bingmei Zhu, Mark Wickre, Maria A. Hoelzl, Sabine Fajmann, Florian Grebien, Wolfgang Warsch, Gabriele Stengl, Lothar Hennighausen, Valeria Poli, Hartm

Journal:

EMBO Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 1.15 MB

english, 2010

11

The aryl hydrocarbon receptor (AhR) and its nuclear translocator (Arnt) are dispensable for normal mammary gland development but are required for fertility

Fabienne Le Provost, Gregory Riedlinger, Sun Hee Yim, Jamie Benedict, Frank J. Gonzalez, Jodi Flaws, Lothar Hennighausen

Journal:

Year:

2002

Language:

english

File:

PDF, 5.55 MB

english, 2002

12

Loss of signal transducer and activator of transcription 5 leads to hepatosteatosis and impaired liver regeneration

Yongzhi Cui, Atsushi Hosui, Rui Sun, Kezhen Shen, Oksana Gavrilova, Weiping Chen, Margaret C. Cam, Bin Gao, Gertraud W. Robinson, Lothar Hennighausen

Journal:

Year:

2007

Language:

english

File:

PDF, 3.77 MB

english, 2007

13

The prospects for domesticating milk protein genes

Lothar Hennighausen

Journal:

Journal of Cellular Biochemistry

Year:

1992

Language:

english

File:

PDF, 801 KB

english, 1992

14

Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system

Dr. Lothar Hennighausen, Robert J. Wall, Urich Tillmann, Minglin Li, Priscilla A. Furth

Journal:

Journal of Cellular Biochemistry

Year:

1995

Language:

english

File:

PDF, 1.33 MB

english, 1995

15

Gene transfer into somatic tissues by jet injection

Priscilla A. Furth, Avi Shamay, Robert J. Wall, Lothar Hennighausen

Journal:

Analytical Biochemistry

Year:

1992

Language:

english

File:

PDF, 1.85 MB

english, 1992

16

Transgenic animals — Production of foreign proteins in milk

Lothar Hennighausen, Leonard Ruiz, Robert Wall

Journal:

Current Opinion in Biotechnology

Year:

1990

Language:

english

File:

PDF, 491 KB

english, 1990

17

MMTV-Cre transgenes can adversely affect lactation: Considerations for conditional gene deletion in mammary tissue

Gertraud W. Robinson, Lothar Hennighausen

Journal:

Analytical Biochemistry

Year:

2011

Language:

english

File:

PDF, 1.00 MB

english, 2011

18

Deficiency in Mouse Oxytocin Prevents Milk Ejection,but not Fertility or Parturition

W. Scott Young III, Emily Shepard, Janet Amico, Lothar Hennighausen, Kay-Uwe Wagner, Mary E. LaMarca, Cindy McKinney, Edward I. Ginns

Journal:

Journal of Neuroendocrinology

Year:

1996

Language:

english

File:

PDF, 514 KB

english, 1996

19

Oxytocin and milk removal are required for post-partum mammary-gland development

Kay-Uwe Wagner, W. Young, Xiuwen Liu, Edward Ginns, Minglin Li, Priscilla Furth, Lothar Hennighausen

Journal:

Genes and Function

Year:

1997

Language:

english

File:

PDF, 829 KB

english, 1997

20

Evaluation of Stat5 as a potential drug target inbcr/abl-induced leukemias

Andrea Hölbl, Christian Schuster, Boris Kovacic, Maria Hölzl, Sabine Fajmann, Florian Grebien, Lothar Hennighausen, Yongzhi Cui, Richard Moriggl, Hartmut Beug, Veronika Sexl

Journal:

BMC Pharmacology

Year:

2008

Language:

english

File:

PDF, 76 KB

english, 2008

21

Erratum

Rekha K. Paleyanda, Da-Wei Zhang, Lothar Hennighausen, Robert A. Mcknight, Henryk Lubon

Journal:

Transgenic Research

Year:

1995

File:

PDF, 105 KB

1995

22

Expression of genomic and cDNA transgenes after co-integration in transgenic mice

Robert A. McKnight, Robert J. Wall, Lothar Hennighausen

Journal:

Transgenic Research

Year:

1995

Language:

english

File:

PDF, 710 KB

english, 1995

23

Regulation of human protein C gene expression by the mouse WAP promoter

Rekha K. Paleyanda, Da-Wei Zhang, Lothar Hennighausen, Robert A. McKnight, Henryk Lubon

Journal:

Transgenic Research

Year:

1994

Language:

english

File:

PDF, 4.80 MB

english, 1994

24

Synthesis and secretion of the mouse whey acidic protein in transgenic sheep

Robert J. Wall, Caird E. Rexroad, Anne Powell, Avi Shamay, Robert McKnight, Lothar Hennighausen

Journal:

Transgenic Research

Year:

1996

Language:

english

File:

PDF, 1.01 MB

english, 1996

25

Expression of the whey acidic protein in transgenic pigs impairs mammary development

Avi Shamay, Vernon G. Pursel, Erby Wilkinson, Robert J. Wall, Lothar Hennighausen

Journal:

Transgenic Research

Year:

1992

Language:

english

File:

PDF, 2.40 MB

english, 1992

26

Studying Development of Disease Through Temporally Controlled Gene Expression in the Salivary Gland

PRISCILLA A. FURTH, MINGLIN LI, LOTHAR HENNIGHAUSEN

Journal:

Annals of the New York Academy of Sciences

Year:

1998

File:

PDF, 2.58 MB

1998

27

Growth hormone–STAT5 regulation of growth, hepatocellular carcinoma, and liver metabolism

Myunggi Baik, Ji Hoon Yu, Lothar Hennighausen

Journal:

Annals of the New York Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 361 KB

english, 2011

28

Mammary gland involution studies with cDNA microarrays

Gangi, Lisa, Owens, Garrison, Humphreys, Robin, Hennighausen, Lothar, Liu, Edison

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 90 KB

english, 1999

29

10.1038/15046

Hennighausen, Lothar, Furth, Priscilla A.

Journal:

Nature Biotechnology

Year:

1999

Language:

english

File:

PDF, 106 KB

english, 1999

30

NF-K B and HIV

HENNIGHAUSEN, LOTHAR, FURTH, PRISCILLAA.

Journal:

Year:

1990

File:

PDF, 271 KB

1990

31

10.1038/6165

Conklin, Bruce R., Redfern, Charles H., Coward, Peter, Degtyarev, Michael Y., Lee, Elena K., Kwa, Andrew T., Hennighausen, Lothar, Bujard, Hermann, Fishman, Glenn I.

Journal:

Nature Biotechnology

Year:

1999

Language:

english

File:

PDF, 243 KB

english, 1999

32

10.1038/8743

Deng, Chu-Xia, Xu, Xiaoling, Wagner, Kay-Uwe, Larson, Denise, Weaver, Zoë, Li, Cuiling, Ried, Thomas, Hennighausen, Lothar, Wynshaw-Boris, Anthony

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 1.25 MB

english, 1999

33

Epithelial Defect in Prostates of Stat5a-Null Mice

Nevalainen, Marja T, Ahonen, Tommi J, Yamashita, Hiroko, Chandrashekar, Varadaraj, Bartke, Andrzej, Grimley, Philip M, Robinson, Gertraud W, Hennighausen, Lothar, Rui, Hallgeir

Journal:

Laboratory Investigation

Year:

2000

Language:

english

File:

PDF, 2.94 MB

english, 2000

34

Transgenic factor VIII: The milky way and beyond

Hennighausen, Lothar

Journal:

Nature Biotechnology

Year:

1997

File:

PDF, 381 KB

1997

35

Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells

Guimond, Martin, Veenstra, Rachelle G, Grindler, David J, Zhang, Hua, Cui, Yongzhi, Murphy, Ryan D, Kim, Su Young, Na, Risu, Hennighausen, Lothar, Kurtulus, Sema

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 1.39 MB

english, 2009

36

Information networks in the mammary gland

Hennighausen, Lothar, Robinson, Gertraud W.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2005

Language:

english

File:

PDF, 602 KB

english, 2005

37

SOCS3 Negatively Regulates the gp130–STAT3 Pathway in Mouse Skin Wound Healing

Ishida, Yuko, Robinson, Gertraud W, Zhu, Bing-Mei, Pacher-Zavisin, Margit, Yoshimura, Akihiko, Murphy, Philip M, Hennighausen, Lothar

Journal:

The Journal of Investigative Dermatology

Year:

2008

Language:

english

File:

PDF, 3.74 MB

english, 2008

38

Genomic architecture and transcriptional activation of the mouse and human tumor susceptibility gene TSG101: Common types of shorter transcripts are true alternative splice variants

Wagner, Kay-Uwe, Dierisseau, Patricia, B Rucker, Edmund, Robinson, Gertraud W, Hennighausen, Lothar

Journal:

Year:

1998

Language:

english

File:

PDF, 902 KB

english, 1998

39

The interactive web-based histology atlas system

Evans, Jai A, Wagner, Ulrike, Santos, Christopher M, Hennighausen, Lothar

Journal:

Year:

2000

Language:

english

File:

PDF, 566 KB

english, 2000

40

Transforming growth factor alpha and mouse models of human breast cancer

Humphreys, Robin C, Hennighausen, Lothar

Journal:

Year:

2000

Language:

english

File:

PDF, 478 KB

english, 2000

41

The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting‡

Cardiff, Robert D, Anver, Miriam R, Gusterson, Barry A, Hennighausen, Lothar, Jensen, Roy A, Merino, Maria J, Rehm, Sabine, Russo, Jose, Tavassoli, Fattaneh A, Wakefield, Lalage M

Journal:

Year:

2000

Language:

english

File:

PDF, 1.92 MB

english, 2000

42

Mouse models for breast cancer

Hennighausen, Lothar

Journal:

Year:

2000

Language:

english

File:

PDF, 69 KB

english, 2000

43

Functional mammary gland development and oncogene-induced tumor formation are not affected by the absence of the retinoblastoma gene

Robinson, Gertraud W, Wagner, Kay-Uwe, Hennighausen, Lothar

Journal:

Year:

2001

Language:

english

File:

PDF, 246 KB

english, 2001

44

Identification of genes differentially expressed in mouse mammary epithelium transformed by an activated β-catenin

Renou, Jean-Pierre, Bierie, Brian, Miyoshi, Keiko, Cui, Yongzhi, Djiane, Jean, Reichenstein, Moshe, Shani, Moshe, Hennighausen, Lothar

Journal:

Year:

2003

Language:

english

File:

PDF, 417 KB

english, 2003

45

Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways

Gallego, Marta I, Bierie, Brian, Hennighausen, Lothar

Journal:

Year:

2003

Language:

english

File:

PDF, 785 KB

english, 2003

46

Molecular mechanisms of hormone controlled gene expression in the breast

Lothar Hennighausen

Journal:

Molecular Biology Reports

Year:

1997

Language:

english

File:

PDF, 169 KB

english, 1997

47

Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice

Kay-Uwe Wagner, Toni Ward, Barbara Davis, Roger Wiseman, Lothar Hennighausen

Journal:

Transgenic Research

Year:

2001

Language:

english

File:

PDF, 504 KB

english, 2001

48

Validation of Transgenic Mammary Cancer Models: Goals of the NCI Mouse Models of Human Cancer Consortium and the Mammary Cancer CD-ROM

Jeffrey E. Green, Robert Cardiff, Lothar Hennighausen, Lalage Wakefield, Ulrike Wagner, Eva Lee, Jeffrey Rosen, Daniel Medina, Alexander Nitkin, Edison Liu

Journal:

Transgenic Research

Year:

2002

Language:

english

File:

PDF, 36 KB

english, 2002

49

Severe position effects imposed on a 1 kb mouse whey acidic protein gene promoter are overcome by heterologous matrix attachment regions

Robert A. McKnight, Mark Spencer, Robert J. Wall, Lothar Hennighausen

Journal:

Molecular Reproduction and Development

Year:

1996

Language:

english

File:

PDF, 984 KB

english, 1996

50

GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways

Hart, Stefan, Fischer, Oliver M., Prenzel, Norbert, Zwick-Wallasch, Esther, Schneider, Matthias, Hennighausen, Lothar, Ullrich, Axel

Journal:

Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 472 KB

english, 2005

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